Meningioma Resection

Depo-Provera and the Risk of Meningioma: If you've been diagnosed with a meningioma linked to Depo-Provera, we’re here to support your journey—through surgical resection, recovery, and the pursuit of justice.

Why choose the Vigna Law Group?

Talk to Dr. Vigna, a Brain Injury Physician and Attorney.

01.

Your initial contact will be with Dr. Greg Vigna, physician-attorney.

02.

Your medical records will be carefully reviewed by experienced nurses and physicians.

03.

Your case will be filed by National Depo-Provera Lawyers and the Vigna Law Group.

When meningiomas are present, stopping progestin-based treatments is often recommended. Studies show tumors may stabilize or shrink once the medication is discontinued.

Complete the form, and Dr. Vigna or one of our experts will review your information and get back to you promptly.

Name
Email Opt-in

Understanding Depo-Provera and the Risk

What is Depo-Provera?

  • A hormone-based birth control injection (medroxyprogesterone acetate) administered every three months.
  • Used by over 74 million women worldwide.

“Depo-Provera increases the risk of developing brain tumors called meningiomas by 5.6 times. These tumors can cause serious disability depending on their size and location. When they grow into critical neurological areas, they may result in hemiparesis, hydrocephalus, seizures, and cognitive decline.”

— Greg Vigna, MD, JD, national malpractice and product liability attorney, retired brain injury physician

Who Makes It?

  • Pfizer

What Did Pfizer Know—and When?

  • 1980s: Research showed meningiomas have progesterone receptors. Depo-Provera binds to these receptors.
  • 1950s: It was known that some meningiomas are hormone-sensitive.
  • 2000s: Studies linked progesterone receptor-positive meningiomas to more favorable (benign) outcomes than aggressive tumors.
  • 2007: These receptor-positive tumors were found to be less likely to recur after surgery.

What We Know Today

  • Prolonged Depo-Provera use is linked to a significantly increased risk of intracranial meningiomas.
  • Women using Depo-Provera face a 5.6-fold increased risk compared to non-users.
    (Source: Roland et al., BMJ 2024)

We represent women who have received four or more injections of Depo-Provera who developed a meningioma (a type of brain tumor).

Greg Vigna, MD, JD

Read The Latest Meningioma Resection News

Vigna Law Group: Depo-Provera Meningioma Claim Filed in Alameda County, California

01/21/2026

 “At some point, physicians can be held liable for prescribing Depo-Provera when there are alternative birth control medications that do not cause mutations that lead to brain tumors. The literature on this is clear,” states Greg Vigna, MD, JD, national malpractice, Depo-Provera attorney. Dr. Greg Vigna, MD, JD, says, “We filed this case because drug […]

Read More...

Pfizer Joined in a Depo-Provera Meningioma Case in California State Court

01/21/2026

“Pfizer, to this day, does not disclose in its warnings that Depo-Provera is mutagenic, despite clear evidence of a dose-dependent increased risk of meningiomas in women injected with the drug for one year or more, and evidence of a specific mutational tendency associated with its use,” states Greg Vigna, MD, JD, national neurological injury attorney. […]

Read More...

Vigna Law Group: Depo-Provera, Physician Liability, and a ‘Delayed’ Dear Doctor Letter

01/21/2026

“Progesterone-only contraception is associated with a shorter progression-free survival in premenopausal women with WHO Grade I meningioma,” states D. Ryan Ormond, MD, Ph.D, Neurosurgery, University of Colorado. What does Dr. Ormond say about the continued use of Depo-Provera after meningioma resection, published in the Journal of Neuro-oncology in 2018? “Compared to patients taking combination or […]

Read More...

Call Us Today (682) 222-8263

©2026 Vigna Law Group | Privacy Policy | Disclaimers

8939 S. Sepulveda Blvd. Suite 102
Los Angeles, CA, 90045

Dr. Greg Vigna, is the principal of Greg Vigna, MD, JD, PLC, a California personal injury law firm, and his law firm has a non-exclusive referral relationship with the attorneys listed within this site. Dr. Vigna, co-counsels with attorneys across the country.

How Can We Help?